Karl Domenic Geissbühler was educated at the School of Decorative Arts in Zürich and later at the Kunsthochschule in Berlin. He started his career as the artistic director of an international advertising agency.
In 1963 he began to work independently for clients, including British Airways. Since 1976 he has created the graphics as well as costumes and ballet sets for the Zürich Opera.
He has received many awards, notably from the biennial in Lahti, Finland (gold and silver medals in 1987) and the triennial in Toyama, Japan (1988); he also earned gold and silver medals from the NY Art Directors Club. Geissbühler has lectured at the Schule für Gestaltung in Basel since 1997.